In Peyote, a woman conceived to suggest Indigenous Mexican ancestry appears beside an Aztec column. Her face stretches into a succession of watchful eyes, while the column bends and undulates, its carved patterns caught in the same distortion. Human features and architectural ornament follow a shared, unstable rhythm.

Warm earth tones contrast with yellow-green eyes, pale drapery, and a turbulent, grey, cloud-filled sky. The tall, narrow canvas heightens the elongation of both figure and column, lending the composition an almost visionary intensity.

The altered perception suggested by the title extends throughout the scene. The woman and the ancient column appear subject to the same mysterious transformation, as though the boundary between observer and observed has begun to dissolve.

Peyote does not illustrate a particular vision or ritual. Instead, it evokes a state in which familiar forms lose their certainty and another order of perception becomes possible. The painting leaves open a fundamental question: does the world change, or does the way we see it?